Hi, I am Qianyi. I come from an ancient city in China named Xi’an, which is the home of the Terra Cotta Warriors. I got my Bachelor Degree from Northwest A&F University, China.
I came to Purdue in 2009 as a Ph.D student, and I joined the laboratory of Professor Jim Forney. My current project is to investigate the role of SUMOylation in the sexual cycle of Tetrahymena thermophila. SUMOylation is a post-translational modification that plays an important role in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle. Tetrahymena is a freshwater clilated protozoan that shows a striking nuclear dimorphism: it has two types of nuclei. The macronuclear genome is formed from the DNA in the diploid germline micronucleus. During macronuclear development extensive double-strand DNA breaks are created and repaired when specific regions of DNA are eliminated from the macronuclear genome. We have preliminary evidence that SUMOylation plays an important role in this process. Gene knockouts and insertions can be generated by homologous recombination in Tetrahymena so I can construct many useful cell lines for my project. I have lots of fun working with Tetrahymena.
My career goal is to pursue a job in the university and become a professor. At Purdue, I have the opportunity to enhance my teaching skills. I currently instruct an undergraduate student in our lab, and I am looking forward to becoming a Teaching Assistant in the department.
On a personal note, I enjoy playing the piano. I started playing six years old although I haven’t played for a very long time. Besides the piano, I also enjoying cooking and travelling. My dream is to make a tour around the world.