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Xiaoqi Liu


  • Professor Biochem/Cancer Rsr
  • Associate Professor of Biochem/Cancer Rsr
BIND Room 290

Selected Publications

Chen, L., Ahmad, N., & Liu, X. (2016). Combining p53 stabilizers with metformin induces synergistic apoptosis through regulation of energy metabolism in castration-resistant prostate cancer. Cell Cycle, 15, 840849.

Chen, L., Li, J., Farah, E., Sarkar, S., Ahmad, N., Gupta, S., . . . Liu, X. (2016). Co-targeting HSP90 and its client proteins for treatment of prostate cancer. Molecular Cancer Therapy, 15(9), 2107-2018. doi:10.1158/1535-7163.MCT-16-0241

Chen, L., Li, Z., Ahmad, N., & Liu, X. (2015). Plk1 phosphorylation of IRS2 prevents premature mitotic exit via AKT inactivation. Biochemistry, 54, 2473-2480.

Li, J., Karki, A., Hodges, K., Ahmad, N., Zoubeidi, A., Strebhardt, K., . . . Liu, X. (2015). Co-targeting Polo-like kinase 1 (Plk1) and Wnt/-catenin signaling pathway in castration-resistant prostate cancer. Mol Cell Biol, 35, 4185–4198. doi:10.1128/MCB.00825-15

Li, Z., Lu, Y., Ahmad, N., Strebhardt, K., & Liu, X. (2015). Low-dose arsenic-mediated metabolic shift is associated with activation of Polo-like kinase 1 (Plk1) Cell Cycle, 14, 3030-3039.

Shao, C., Ahmad, N., Hodges, K., Kuang, S., Ratliff, T., & Liu, X. (2015). Inhibition of Polo-like kinase 1 (Plk1) enhances the antineoplastic activity of metformin in prostate cancer. J. Biol. Chem, 290, 2024-2033. Retrieved from

Shao, T., & Liu, X. (2015). Identification of Rictor as a Novel Substrate of Polo-like kinase 1. Cell Cycle, 14, 755-760.

Zhang, Z., Chen, L., Wang, H., Ahmad, N., & Liu, X. (2015). Inhibition of Plk1 represses androgen signaling pathway in castration-resistant prostate cancer. Cell Cycle, 14, 2142-2148.

Li, Z., Li, J., Bi, P., Lu, Y., Burcham, G., Elzey, B., . . . Liu, X. (2014). Plk1 phosphorylation of PTEN causes a tumor-promoting metabolic state. Mol. Cell Biol, 34(19), 3642-3661. Retrieved from

Awards & Honors

(2016) Faculty Scholar. Purdue University.

(2016) Purdue Cancer Research Award. Lafayette Lions Club.

(2013) The American Cancer Society Research Scholar. The American Cancer Society.

(2005) Howard Temin Award. NIH.

(2004) Don Wiley Award provided. Merck.

Department of Biochemistry, 175 South University Street, West Lafayette, IN 47907-2063 USA, (765) 494-1600

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