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Gunter Kohlhaw


 Gunter Kohlhaw


Emeritus Professor of Biochemistry

Department: Biochemistry

Area of Expertise: Regulation of leucine biosynthesis in bacteria and yeast

Retired: 1998

Cirriculum Vitae





Wang, D., Zheng, F., Holmberg, S., and Kohlhaw, G. B. Yeast transcriptional regulator Leu3p: Self-masking, specificity of masking and evidence for regulation by the intracellular level of Leu3p. J. Biol. Chem. 274 in press (1999).

Wang, D., Hu, Y., Zheng, F., Zhou, K., and Kohlhaw, G. B. Evidence that Intramolecular Interactions are Involved in Masking the Activation Domain of Transcriptional Activator Leu3p. J. Biol. Chem. 272, 19383-19392 (1997).  
Guo, H. and Kohlhaw, G. B. Regulation of transcription in mammalian cells by yeast Leu3p and externally supplied inducer. FEBS Letters 390, 191-195 (1996).  
Hu, Y. and Kohlhaw, G. B. Additive activation of yeast LEU4 transcription by multiple cis elements. J. Biol. Chem. 270, 5270-5275 (1995).  
Hu, Y., Cooper, T. G., and Kohlhaw, G. B. The Saccharomyces cerevisiae Leu3 protein activates expression of GDH1, a key gene in nitrogen assimilation. Mol. Cell. Biol. 15, 52-57 (1995)   
Remboutsika, E., and Kohlhaw, G. B. Molecular architecture of a Leu3p-DNA complex in solution: A biochemical approach. Mol. Cell. Biol. 14, 5547-5557 (1994).  

Sze, J., Remboutsika, E., and Kohlhaw, G. B. Transcriptional regulator Leu3 of yeast: Separation of activator and repressor functions. Mol. Cell. Biol. 13, 5702-5709 (1993).

Sze, J., and Kohlhaw, G. B. Purification and structural characterization of transcriptional activator Leu3 of yeast. J. Biol. Chem. 268, 2505-2512 (1993).  
Sze, J., Woonter, M., Jaehning, J. and Kohlhaw, G. B. In vitro transcriptional activation by a metabolic intermediate: Leu3-dependent activation requires α-isopropylmalate. Science 258, 1143-1145 (1992).   
Bai, Y. and Kohlhaw, G. B. Manipulation of the zinc finger-like region of transcriptional activator LEU3 by site-directed mutagenesis. Nucl. Acids Res. 19, 5991-5997 (1991).