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March 2014 Issue
Kim, J.I., P.N. Ciesielski, B.S. Donohoe, C. Chapple and X. Li. 2014. Chemically induced conditional rescue of the reduced epidermal fluorescence8 mutant of Arabidopsis reveals rapid restoration of growth and selective turnover of secondary metabolite pools. Plant Physiol. 164: 584-595.
Yue, S., J. Li, S.-Y. Lee, H.J. Lee, T. Shao, B. Song, L. Cheng, T.A. Masterson, X. Liu, T.L. Ratliff and J.-X. Cheng. 2014. Cholesteryl ester accumulation induced by PTEN loss and PI3K/AKT activation underlies human prostate cancer aggressiveness. Cell Metab. 19: 393-406.
Mohan, R.D., G. Dialynas, V.M. Weake, J. Liu, S. Martin-Brown, L. Florens, M.P. Washburn, J.L. Workman and S.M. Abmayr. 2014. Loss of Drosophila Ataxin-7, a SAGA subunit, reduces H2B ubiquitination and leads to neural and retinal degeneration. Genes Dev. 28: 259-272.
Sullivan, K.L., L.C. Huma, E.A. Mullins, M.E. Johnson and T.J. Kappock. 2014. Metal stopping reagents facilitate discontinuous activity assays of the de novo purine biosynthesis enzyme PurE. Anal. Biochem. 452: 43-45.
Ma, W.K., S.C. Cloutier and E.J. Tran. 2014. The DEAD-box protein Dbp2 functions with the RNA-binding protein Yra1 to promote mRNP assembly. J. Mol. Biol. 425: 3824-3838.
Saatchi F. and A.L. Kirchmaier. 2013. HATs, HDACs and the regulation of cellular processes in Acetate: Versatile Building Block of Biology and Chemistry. (D.A. Sanders Ed.), Nova Science Publishers, Inc., pp. 29-64.
Awards & Recognition

Dean Jay Akridge surprised Barb Golden during the seminar series on March 11 to announce that she was selected as a 2014 University Faculty Scholar. The University Faculty Scholar program sponsored by the Office of the Provost is designed to recognize outstanding faculty members across the university who are on an accelerated path for academic distinction. Faculty Scholars are appointed for a nonrenewable five-year term and receive an annual $10,000 discretionary allocation. Barb joins Scott Briggs, Ann Kirchmaier, and Andy Tao who are also Faculty Scholars.
Jesse Murphy (Kappock lab) is this year’s Outstanding TA in Biochemistry. The award is given annually to recognize a student’s outstanding performance as a teaching assistant. He is recognized for his work in BCHM 309 (Biochemistry lab) during the fall 2013 semester. Jesse’s confidence allowed him to prepare lecture materials and lead a number of lab session himself. His enthusiasm for the subject matter was evident and helped engage the students in topics that they might otherwise have trouble understanding. His tireless work with students from all sections of the course was critical to altering attitudes towards the subject matter. Jesse will be recognized at the Celebration of Teaching Excellence banquet hosted by the Center for Instructional Excellence on April 30.
Clint Chapple and his lab members were featured in Purdue Today for their discovery that could yield more efficient plants for biofuels.
Sherry Pogranichniy received a professional development grant from the Purdue Academic Advising Association (PACADA) for her travels noted below.
Vikki Weake received a grant in the amount of $9,900 from the Indiana Clinical and Translational Sciences Institute (CTSI) Core Pilot Proposal program for her project entitled, “Epigenetic maintenance of gene expression homeostasis in the aging eye” (03/17/2014 – 03/16/2016).
In December, the department was awarded $4,900 from the Ag Alumni Trust Fund for the purchase of a new poster printer. The HP DesignJet T790 printer was installed this month!
Saying Goodbye

Steve Widger will be retiring from the department on April 25. Steve started his Purdue career in 2000 as a storekeeper in the Department of Biological Sciences and has been a member of our biochemistry storeroom since July 2005. Steve plans to travel south a lot over the next couple of years in search of the perfect retirement spot in Tennessee or Georgia. He’s anxious to get to things that he never has time to do, as well as continue with his freelance ceramics, volunteering at Natalie’s Second Chance dog rescue, and taking care of his own four dogs. Steve will miss everyone he has worked and interacted with, but he will especially miss the two people he has spent the last nine years with, Linda Siersema and Don Fultz. Steve says, “Thank you, Linda. You were one of the best supervisors to work for.”
 New Faces

Qiuju (Sarah) Zhang joined the Kappock lab on March 1 as a Research Assistant. Sarah was born in Wuhan, Hubei province in China and she received her Ph.D. in genetics from Wuhan University in 2007. Prior to joining the Kappock lab, she was a research associate in Dr. Jue Chen’s lab in the Department of Biological Sciences at Purdue.
Graduate Student News

Andrew Huh (Clemens lab) will graduate in May, but is leaving the department on March 31. He will be moving to California to begin his postdoctoral work in the Department of Pathology at Stanford University working with Dr. Bingwei Lu. 
Nina Serratore (Briggs lab) passed her preliminary examination on February 28. 
Chris Petell (Gowher lab) passed his preliminary examination on March 24. 
Graduate student Kit Ma (Tran lab) coordinated an information session with Lanthana Ubayasena and David Isenhour from Dow AgroSciences on March 13. They shared with the graduate students and postdocs their working experiences in industry and what kind of skill sets Dow AgroSciences is looking for.  Dr. Ubayasena is a molecular biologist and Dr. Isenhour is a talent manager in R&D.
Alumni News
Carl Burtis (Ph.D. 1967, H.D. Jackson, major professor; Honorary Doctorate of Science from Purdue University. 2004) received a 2014 International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) award. These distinguished awards are presented by the IFCC to laboratory medicine professionals to recognize their outstanding achievements, publicize their exceptional research and contributions to medicine and healthcare, and encourage the overall advancement of clinical chemistry and laboratory medicine. Carl is retired from the Oak Ridge National Laboratory and he was honored with the 2014 IFCC Award for Distinguished Contributions in Education for his extraordinary contribution to the profession of clinical chemistry as editor of the “Tietz Textbook of Clinical Chemistry and Molecular Diagnostics,” which he has developed into one of the premier compilations of educational material used in the field today.
Tuajuana Jordan (Ph.D. 1989, Rodwell) was selected to become the 7th president at St. Mary’s College of Maryland effective July 1. Tuajuana is currently the dean of the College of Arts and Sciences and professor of chemistry at Lewis & Clark College in Portland, OR. In 2008, she received the Distinguished Agricultural Alumni Award for Biochemistry.
Gloria Muday (Ph.D. 1989, Herrmann) was one of six recipients on campus to receive a 2014 Distinguished Women Scholars award. The awards program, led by Purdue's Office of the Provost in partnership with Discovery Park’s Susan Bulkeley Butler Center for Leadership Excellence, honors alumnae who earned a Purdue doctorate and have made significant scholarly contributions to their academic communities. Gloria is a professor and the Director, Center for Molecular Communication and Signaling in the Department of Biology at Wake Forest University.
Kayleigh Nyfeller (B.S. 2013) will continue her studies as she enters the Microbiology Ph.D. program in the Department of Bacteriology at the University of Wisconsin-Madison this fall.
The Lafayette Regional Science and Engineering Fair
This year’s Lafayette Regional Science and Engineering Fair was held on March 7. Volunteer judges spent time talking to 500 plus students in grades 5-12 from 20 area schools about their scientific experiments. The biochemistry department had several representatives at the fair:
Dr. Orla Hart
Dr. Sandra Rossie
Graduate Students:
Nick Anderson
Ben Carter
Yi Li
Jessie Murphy
Kelly Sullivan
Going the Extra Mile
Barbara Golden traveled to Washington, DC, to serve on an NIH Macromolecular Structure and Function B review panel.
Sherry Pogranichniy traveled to Madison, WI, to attend the Region 5 meeting of the National Academic Advising Association (NACADA).
IT Corner by Joe Levell
This month I would like to remind everyone to back up your data before something disastrous happens.  There are various methods you can use, but I suggest you follow the system below.
The best way to back up your data properly is to use the 3-2-1 rule.
•             Keep 3 copies of anything you care about.
•             Keep the files on at least 2 different media types (external hard drive, networked hard drive, cd/dvd, flash drive, etc.)
•             Keep 1 copy stored off-site on one of the above media types and kept in a safe location.
Here is a practical example.
You need to back up the file "research_picture.jpg" and this file is stored on your laptop in your documents folder. 
1. Make a copy and place it on the departmental shared network server, S:
2. Make another copy and place it on a flash drive.
3. Make the final copy and put it on a cd/dvd, flash drive, or external hard drive and store it somewhere safe off-campus.***
***You may want to have two sets of #3 an A and a B. This way you always have the ability to backup when you need to and don’t have to retrieve your media from the off-site location before you do a backup.
It’s up to you how often you do this.  I suggest that you do this weekly at the end of the week.
Safety Corner by Karyn Rodkey
In addition to picking up Hazardous Chemical Waste, REM will come to your lab and pickup old and unused chemicals. The easiest method is to go to their online submission form.
It is important to note that fume hood bench space should not be used for research AND storage. This will be a citation during a REM safety inspection. Hoods should be clear of bottles containing chemicals (including waste) unless the bottles are for an ongoing experiment for which the researcher is standing there using them. The hood is also not to be used for storing equipment.
When storing bottles of chemicals remember: (1) Some non-compatible chemicals can be stored in the same cabinet, but separated by a secondary container. (2) Some “hazardous chemicals” can be stored in cabinets other than fume hood cabinets. Save the fume hood cabinets for the more volatile, and “smelly” chemicals.
Please do not hesitate to call REM with any and all questions pertaining to chemical storage! 49-40121
Ji Chen
Ann Kirchmaier
Jie Li
Jesse Murphy
Li Pan
Beth Tran
Lee Weith
Cindy Xing
Upcoming Events
April 1                   BCHM Seminar
                              Christina Hrycyna
                              WSLR 116, 3:30PM
April 8                   BCHM Seminar
                               Phillip Zamore
                               LYNN 1136, 3:30PM
April 15                 BCHM Seminar 
                               Beth Tran
                               WSLR 116, 3:30PM
April 22 & 23        Axelrod Lectures
                               Kathleen Gould
                               April 22: Deans Auditorium (PFEN 241), 3:30PM
                               April 23: Deans Auditorium (PFEN 241), 4:00PM
April 29                 Biochemistry Spring Award Convocation
                               WSLR 116, 3:30PM