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Daniel B Szymanski

Botany and Plant Pathology 

  • Professor
WSLR, Room 226

 General Information

Dan Szymanski’s lab in collaboration with labs in biological and mechanical engineering combines experimental and computational biology to discover how plant cells dynamically reorganize the cytoskeleton and the cell wall during cell morphogenesis. Iterative cycles of multivariate live cell imaging, finite element computational modeling is leading to realistic and predictive models of plant cell growth control that are enabling crop plant engineering. Another major project in the lab is to develop a proteomics pipeline that can be used to discover and analyze endogenous protein complexes and how they change in response to environmental and developmental conditions.

Editorial Board Member

Plant Physiology

Frontiers in Plant Cell Biology

in silico Plants

Refereed Journal Articles (Google scholar page)

  • Yanagisawa, M., Desyatova, A.S., Belteton, S., Mallery. E. M, Turner, J.A., Szymanski, D. B. 2015 Patterning mechanisms of cytoskeletal and cell wall systems during leaf trichome morphogenesis. Nature Plant 1:15014. 
  • Wu, T.-Z., Belteton, S., Lunsford, J., Szymanski, D.B., Umulis, D.B. 2016  Quantitative image analysis of pavement cell morphogenesis with LobeFinder. Plant Physiol. 171:2331-2342. 
  • Uma, A., McBride, Z., Chen, D., Xie, J., Szymanski, D.B. 2017 Analysis of protein complexes in Arabidopsis leaves using size exclusion chromatography and label-free protein correlation profiling, Journal of Proteomics. 166:8-18.  
  • McBride, Z., Chen, D., Reick, C., Xie, J., Szymanski, D.B., 2017 Global analysis of membrane-associated protein oligomerization using protein correlation profiling.  Mol Cell Proteomics. 16:1972–1989. 
  • Belteton, S., et al. 2018 Reassessing the roles of PIN proteins and anticlinal microtubules during pavement cell morphogenesis. Plant Physiol. 176:432-449. 10.1104/pp.17.01554 
  • Yanagisawa, M., Alonso, J.M., and Szymanski, D.B. 2018 Microtubule-dependent confinement of a cell signaling and actin polymerization control module regulates polarized cell growth. Current Biol 28, 2459-2466.
  • McBride, Z., Chen, D., Lee, Y., Aryal, U., Xie, J., Szymanski, D.B., 2019 A label free mass spectrometry method to predict endogenous protein complex composition.  Mol Cell Proteomics. 18: 1588-1606. 
  • Lee, Y., and Szymanski, D.B. 2021 Multimerization variants as potential drivers of neofunctionalization. Science Advances 7: eabf0984.
  • Belteton, S., Lee, W., Hatam, F.A., Szymanski, M.R., Marley, M.W., Turner, J.A., and Szymanski, D.B.2021 Real-time conversion of tissue-scale mechanical forces into an interdigitated growth pattern. Nature Plants 7, 826-841.

Review Articles

  • Szymanski, D.B. 2016 Math plus biology: building a knowledge base to engineer plant traits  Scientia 109.
  • Szymanski, D. B., et al. 2018 Cellular dynamics: cellular systems in the time domain." Plant Physiol 176: 12-15.
  • Szymanski, D. B. and C. J. Staiger 2018 The actin cytoskeleton: functional arrays for cytoplasmic organization and cell shape control. Plant Physiol. 176: 106-118.
  • Li, J., Kim, T., and Szymanski, D.B. 2019 Multi-scale regulation of cell branching: Modeling morphogenesis. Dev Biol 451, 40-52.

Botany and Plant Pathology, 915 West State Street, West Lafayette, IN 47907 USA, (765) 494-4614

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