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Chunhua Zhang

 General Information

Plant vesicle trafficking plays fundamental roles in growth, development and response to environment stimuli. My lab develops small molecule inhibitors that interfere with plant vesicle trafficking and use these inhibitors as tools to understand the molecular and cellular mechanisms of plant vesicle trafficking under normal growth conditions and stressed environment stimulations. Currently, we are using Endosidin2, a small molecule that targets the Exo70 subunit of the exocyst complex to inhibit plant exocytosis, to understand how exocyst complex functions together with other cellular components to control plant exocytosis in a spatiotemporal manner. We also use Endosidin20, a small molecule that targets the cellulose synthase to inhibit cellulose biosynthesis, to understand how the enzymatic activity of plant protein complexes affects their subcellular transport.    

Botany and Plant Pathology, 915 West State Street, West Lafayette, IN 47907 USA, (765) 494-4614

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