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ENTM News: Hongmei Li-Byarlay (PhD '07) publishes research

Title

Hongmei Li-Byarlay (PhD '07) publishes research

Body

Purdue alumna Hongmei Li-Byarlay has published her research on honeybee fruit fly brain metabolism and aggression.  "Despite high energetic demands in the brain, glucose is not always metabolized to produce maximum energy. Aerobic glycolysis, that is, high levels of glucose consumption relative to oxygen use, is connected to cognition and disease, but metabolic plasticity remains challenging to study in vivo owing to the brain’s complexity. We show that decreased oxidative phosphorylation activity, a pattern that resembles aerobic glycolysis, causes increased aggression in honey bees and fruit flies. This effect is specific to neurons and not glia, and the social environment modulates the relationship between metabolism and aggression. The fly–bee system, linking variation in brain metabolism to a natural behavior, could be used to further study the function of brain metabolic plasticity."

 

The collaborative paper is published in the July 2, 2014 issue of PNAS Early Edition.

Expires

 

Summary

Purdue alumna Hongmei Li-Byarlay has published her research on honeybee fruit fly brain metabolism and aggression.  "Despite high energetic demands in the brain, glucose is not always metabolized to produce maximum energy. Aerobic glycolysis, that is, high levels of glucose consumption relative to oxygen use, is connected to cognition and disease, but metabolic plasticity remains challenging to study in vivo owing to the brain’s complexity. We show that decreased oxidative phosphorylation activity, a pattern that resembles aerobic glycolysis, causes increased aggression in honey bees and fruit flies. This effect is specific to neurons and not glia, and the social environment modulates the relationship between metabolism and aggression. The fly–bee system, linking variation in brain metabolism to a natural behavior, could be used to further study the function of brain metabolic plasticity."

 
The collaborative paper is published in the July 2, 2014 issue of PNAS Early Edition.

Author

​Hongmei Li-Byarlay

Date Added

8/8/2014

Attachments

Created at 8/19/2014 4:08 PM by York, Beth B
Last modified at 8/19/2014 4:08 PM by York, Beth B