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Stephen R Lindemann

Department of Food Sciences 

  • Assistant Professor Food & Nutrition Sci
Nelson Hall of Food Science (NLSN) Room 3215
745 Agriculture Mall Drive
West Lafayette, IN 47907

Foods and Nutrition 

  • Assistant Professor Food & Nutrition Sci

Dr. Lindemann's research targets ways that diet influences the gut microbiome and the effects of those shifts in that gut colony of microorganisms have on health, such as inflammation and gut colonization by pathogens. The goal is to discover dietary solutions to health problems such as Crohn's disease, diabetes, inflammatory bowel disease, colorectal cancer, ulcerative colitis and more. Specifically, Dr. Lindemann's lab focuses on using molecular ecology techniques to understand how diet influences the composition and stability of the gut microbiome; how gut microbiome metabolism of dietary components influences production and absorption of bioactive microbial metabolites; how metabolic interactions between microbes alter polysaccharide fermentation and nitrogen metabolism in the colon; and how these interactions between beneficial microbes exclude pathogenic organisms and modulate inflammation in the colon. 

Current Graduate Students and Research Lab Members

Selected Publications

Tuncil, Y., Chen, M., Yao, T., & Lindemann, S. R. (2018). Polysaccharide chemical structure controls on fermentation by gut microbiota, metabolic outputs, and interspecies interactions. American Chemical Society, 255.

Lindemann, S. R. (2019). Microbial Ecology: Functional “Modules” Drive Assembly of PolysaccharideDegrading Marine Microbial Communities. 29(9), R330-332.

Song, H. S., Renslow, R. S., Fredrickson, J. K., & Lindemann, S. R. (2015). Integrating ecological and engineering concepts of resilience in microbial communities. Front. Microbiol, 6, 1298.

Nelson, W. C., Maezato, Y., Wu, Y. W., Romine, M. F., & Lindemann, S. R. (2016). Metagenomic sequencing of parallel consortia enables genome reconstruction of rare and closely-related organisms. AEM, 82(1), 255-267.

Renslow, R. S., Lindemann, S. R., & Song, H. S. (2016). A generalized spatial measure for resilience of microbial systems. Front. Microbiol, 7, 443.

Cole, J. K., Morton, B. R., Cardamone, H. C., Lake, H. R., Dohnalkova, A. C., Kim, Y. M., . . . Lindemann, S. R. (2018). Saliniramus fredricksonii gen. nov., sp. nov., a heterotrophic halophile isolated from Hot Lake, Washington, a member of a novel lineage (Salinarimonadaceae fam. nov.) within the order Rhizobiales, and reclassification of the genus Salinarimonas Liu et al. 2010 into Salinarimonadaceae. International Journal of Systematic and Evolutionary Microbiology, 68(6), 2116-2123.

Rosnow, J. R., Nandhikonda, P., Killinger, B., Nair, R., Anderson, L., Kim, Y. M., . . . Wright, A. (2018). Elucidating the mechanistic underpinnings of a cobalamin activitybased probe in microbial cell growth, gene regulation, and enzyme activity. Applied and Environmental Microbiology, 84, 18.

Biruete, A. K., Gallant, H., Lindemann, S. R., Wiese, G., Chen, N., & Moe, S. (in press). Phosphate binders and non-phosphate effects in the gastrointestinal tract. Journal of Renal Nutrition.

Song, H. S., Lee, J. Y., Haruta, S., Nelson, W., Lee, D. Y., Lindemann, S. R., . . . Bernstein, H. (2019). Minimal Interspecies Interaction Adjustment (MIIA): inference of member-dependent interactions in microbiomes. Frontiers in Microbiology, 10, 1264.

Bohutskyi, P., McClure, R. S., Hill, E. S., Nelson, W. C., Chrisler, W. B., Nunez, J. R., . . . Beliaev, A. S. (2019). Metabolic Effects of Vitamin B12 on Cyanobacterium stanieri Physiology, Stress Resistance, and Biofilm Organization. Algal Research, 42, 101580.

Department of Food Science, 745 Agriculture Mall Drive, West Lafayette, IN 47907, (765) 494-8256

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