Seed-based technology offers peace of mind from sorghum forage risk

S

orghum has served as a food and feed crop for thousands of years, yet it can become poisonous under drought or freezing conditions. The problem is dhurrin, which breaks down to form prussic acid, also known as hydrogen cyanide.

But Purdue University’s Mitch Tuinstra, professor of plant breeding and genetics and scientific director of the Institute for Plant Sciences, has developed a dhurrin-free sorghum technology that will set farmers’ minds at ease. The S&W Seed Company of Longmont, Colo., has licensed the technology, which will be widely available to growers in 2023.

“Cyanide poisoning is something that people who graze cattle on sorghum always have to be concerned about. It doesn’t happen all that often. But when it does happen it’s a serious thing. This technology eliminates that risk,” said Brent Bean, director of agronomy at the United Sorghum Checkoff Program in Lubbock, Texas. USCP is a producer-funded organization dedicated to improving the sorghum industry through research, promotion, and education.

At $1,300 or more per steer, cattle are a big investment.

“You lose even one, that is a big downside to the bottom line,” Bean said.

Making cyanide helps sorghum fend off chewing insects and grazing animals. But farmers still use sorghum as a forage crop because it works well in high temperatures, it tolerates drought, and it produces a lot of feed with fairly minimal input.

 

Sorghum field in west Texas A field in west Texas where S&W Seed Company is testing a prussic acid-free sorghum developed by Purdue’s Mitch Tuinstra. Credit: Scott Staggenborg/S&W

“Sorghum is grown where it’s too hot and dry to grow other crops,” said Tuinstra, who also is Purdue’s Wickersham Chair of Excellence in Agriculture Research. “It’s grown where you don’t have other options. You can’t grow corn in these environments because it is not adapted.”

Farmers who grow sorghum in such environments have to manage it carefully to minimize the risk.

“Every farmer I talk to has stories about animals having problems with prussic acid. This is a technology that can help alleviate that concern.”

Tuinstra pictured forage breeder and molecular lab director of S&W Seed Company in sorghum trial fields Purdue’s Mitch Tuinstra (center), discusses the progress of prussic-acid free sorghum tests in west Texas with forage breeder Mauricio Barbosa (left) and molecular lab director Wayne Shen, both of S&W Seed Company. Credit: Scott Staggenborg/S&W

Tuinstra began thinking about removing dhurrin from sorghum in late 2008.

“I thought that would be interesting because we know the genes, the enzymes, the biochemistry, but many questions about dhurrin metabolism remain unanswered,” Tuinstra said. “So, the next summer, we started producing the genetic materials for this study.”

Sorghum is used worldwide, including in Africa, Australia, North and South America, and South Asia.

“Sorghum is an important crop in any place you have a hot, dry climate. And with climate change, that’s potentially very important,” said Jay Hulbert, president, and CEO of Ag Alumni Seed in Romney, Ind. “There are areas in the U.S. and globally where people grow other crops, especially corn, where they’d probably be better off growing sorghum.”

Scott Staggenborg, S&W’s Sorghum product marketing manager for the Americas, expressed excitement for the technology because it solves a problem in a widely used product. Growers are also enthused.

“I have people saying, ‘I’ll buy every bag you have,” Staggenborg said. He noted that the technology can work in any type of sorghum, including sorghum-sudangrass, a summer annual with a robust yield that is hard to match.

“Lots of cattle are grown in semi-arid and arid environments. Sorghum-sudangrass is important globally because of its drought tolerance and heat tolerance.”

Tuinstra partnered with Hulbert to develop prototype varieties, a patent and a business plan for the technology. They had considered launching a seed company in Indiana, but they learned that sorghum seed production works better in dry climates.

“Indiana is great for a lot of things, but not necessarily for making sorghum seed on a large scale,” Hulbert said. This led them to the S&W Seed Company, which is running trials this year in west Texas on Tuinstra’s most promising hybrids.

“This is a classic example of how university research is supposed to work,” Hulbert said. “Mitch had an idea and started working on something successful that none of the sorghum seed companies were working on. Then we find a way to take it to farmers through commercial channels to the private sector.”

Another key aspect of the technology was working with the Indiana Crop Improvement Association, an agency that certifies seed quality. The ICIA patented a new seed quality assay using dhurrin-free sorghum as the prototype. The assay makes it possible to test large lots of seed with a high-tech, DNA sequencing-based approach to quality assurance.    

“At Purdue University, we’re interested in developing transformative technologies that solve farmer challenges, and we’re trying to do that very broadly within Indiana, the U.S. and internationally,” Tuinstra said.

Featured Stories

Lab photo of mosquito larva.
Purdue-Enveda effort seeks to control malaria-spreading mosquitoes

Purdue University is leading a $1.7 million project funded by the Gates Foundation to develop new...

Read More
Caitlin Proctor stands next to the Overbeck Controlled Environment Agricultural Facility’s vertical hydroponic system
Purdue engineer receives major USDA AFRI Award

Hydroponics – growing crops in nutrient-enriched water instead of soil – is a...

Read More
Sophie Low measures a bird during a bird-banding experience; Sophie Low
Meet Outstanding Freshman Sophie Low

Sophie Low, a wildlife major with a minor in forensic science, was selected as FNR's...

Read More
Five middle-aged colleagues wearing business casual attire sitting at a table with laptops and a whiteboard in the background.
Reimagining food science through applied AI

Artificial intelligence (AI) is transforming the global food system — from how crops are...

Read More
2026 Consumer Food Safety Education webinar featuring three speakers; July 1, 8, and 15 via Zoom.
Webinar Series – 2026 Summer School for Consumer Food Safety Education

The Food Safety Human Factor Lab within the Department of Food Science at Purdue University is...

Read More
Aya Hussain in greenhouse with lettuce.
Aquaponics project seeks to boost Midwest seafood production

Half a billion years ago, a shallow sea covered an equatorial landmass today known as Indiana and...

Read More